In a saucepan, combine the hot sauce, butter, white vinegar, Worcestershire sauce, garlic powder, and cayenne pepper.
Place the saucepan over medium heat and cook, stirring occasionally, until the butter is melted and the ingredients are well combined, about 5 minutes.
Remove from heat, season with salt to taste, and allow the sauce to cool slightly before using.
If not using immediately, store the buffalo sauce in an airtight container in the refrigerator.