Go Back
+ servings
Greek Pastitsio Casserole Recipe

Greek Pastitsio Casserole Recipe

Angela Sellari
This recipe Greek Pastitsio Casserole is perfect to make on the weekend and have ready for a busy weeknight. You can easily make it ahead. Just assemble everything in the afternoon, and then put it in the oven to warm it through and melt the cheese at dinner time.
5 from 2 votes
Prep Time 20 minutes
Cook Time 5 minutes
Total Time 25 minutes
Course main
Cuisine European
Servings 10
Calories 326 kcal

Ingredients
  

  • 12 ounces penne pasta
  • 1 1/2 pounds ground sirloin
  • 1 1/2 cups yellow or white onion chopped (1 large onion)
  • 1 3/4 teaspoons salt divided
  • 1 teaspoon pepper
  • 1 teaspoon Italian seasoning
  • 6 garlic cloves finely minced
  • 2 tablespoons all-purpose flour
  • 8 ounces reduced-fat cream cheese
  • 2 cups low-fat milk
  • 1/4 teaspoon nutmeg
  • 1/2 teaspoon allspice
  • 1/2 teaspoon cinnamon
  • 1 14.5 ounces can diced tomatoes, drained
  • 1 cups shredded part-skim mozzarella cheese
  • 2 tablespoons chopped fresh flat-leaf parsley

Instructions
 

  • Coat a 9X13-inch or equivalent baking dish with cooking spray and set aside. Preheat oven to 350 degrees.
  • In a large pot of lightly salted, boiling water, cook the penne pasta according to package directions.
  • While the pasta is cooking, heat a large 12-inch skillet over medium heat. Add beef or turkey to the pan with the diced onions and 1 teaspoon salt and pepper. Cook, stirring to break up the meat into small pieces, until the meat is cooked through. Drain excess grease from the meat. Add the garlic and cook until fragrant, another minute or so.
  • Sprinkle the flour over the meat mixture, stirring to combine, and cook for 1-2 minutes over medium heat. Add the cream cheese in pieces, scattering it over the meat. Let it melt into the meat and stir to combine.
  • Whisk or stir in the milk, nutmeg, allspice, cinnamon, 3/4 teaspoon salt, Italian seasoning and tomatoes. Stir to combine and bring the mixture to a simmer. Cook 5-6 minutes until the mixture is slightly thickened and is thoroughly heated through.
  • Stir in the pasta and spoon the pasta mixture into the prepared pan. Sprinkle the mozzarella cheese evenly over the pasta and bake for 15 – 20 minutes, until the cheese is starting to brown (watching carefully so it doesn’t burn).
  • Remove from the oven and sprinkle with parsley. Let it stand for about 5 minutes before serving.

Nutrition

Calories: 326kcalCarbohydrates: 21gProtein: 21gFat: 17gSaturated Fat: 8gSodium: 628mgFiber: 2g
Keyword Greek Pastitsio Casserole Recipe
Tried this recipe?Let us know how it was!