Pat the shrimp dry using paper towels. Next, combine garlic powder, onion powder, salt, and pepper in a bowl, then add the shrimp to evenly coat them with the seasoning.
Heat a large skillet over high heat and melt 2 tablespoons of butter. Add the shrimp and cook for about 2 minutes until browned.
Reduce heat to medium-low and stir in 2 teaspoons of lemon juice, then season with more salt and pepper to taste.
Cook for about 1 minute until the shrimp are heated through. Remove from heat and stir in the remaining 2 tablespoons of butter. Garnish with parsley and serve with lemon wedges for squeezing extra lemon juice on top.