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HomeMealtimeRecipes

Southwestern Turkey Casserole

4.90 from 19 votes
Angela SellariBy Angela Sellari
Angela Sellari
Angela Sellari Founder of AboutAMom

Angela is the founder of About A Mom and currently acts as a content creator and editor-in-chief for the About A Mom Team. She has been a professional blogger for over 10 years. Angela has appeared…

Expertise: Content Creation & Editing View all posts →
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Pretty soon you’ll be wondering what to do with all that leftover Thanksgiving or Christmas turkey.

Southwestern Turkey Casserole is a great recipe to use up turkey leftovers!

Turkey sandwiches are always great, but they get so boring after a couple of days. Instead use some of that leftover turkey to make a delicious meal like this Southwestern Turkey Casserole. Last week Mom and I prepared our Citrus and Herb Turkey, and then used some of the leftovers for this casserole. It was delicious, and I think I might have enjoyed the casserole more than the traditional turkey dinner we ate.

This casserole can be prepared in one large 13 inch x 19 inch baking dish. We opted to make 2 smaller casseroles. One to keep and one to send over to my brother’s house. The recipe can easily be halved – the beauty of a casserole. Since this dish has crushed tortilla chips, I recommend serving the same day it is prepared so the chips keep their crunch. I love that added texture.

Southwestern Turkey Casserole is a great recipe for using up holiday turkey leftovers.

Ingredients:

  • 2 large onions, chopped
  • 1 green pepper, chopped
  • 2 tablespoons butter
  • 6 cups cubed cooked turkey
  • 2 cans (10-3/4 ounces each) condensed cream of chicken soup, undiluted
  • 2 cups (16 ounces) sour cream
  • 1 package (10 ounces) frozen chopped spinach, thawed and squeezed dry
  • 2 cups (8 ounces) shredded Monterey Jack or cheese blend
  • 1 package (12-1/2 ounces) tortilla chips, crushed

Instructions:

Step 1: Prepare greased 13 inch x 9 inch baking dish. In a medium size pot, saute onions and green pepper in butter until tender. Stir in the turkey, soup, sour cream and spinach. Spoon half of the turkey mixture into the baking dish. Then a layer of cheese and tortilla chips. Repeat layers.

Step 2: Bake casserole, uncovered, at 350 degrees for 25-30 minutes or until bubbly. Let stand for 5 minutes before serving.

Enjoy! What’s your favorite turkey leftovers recipe?

Southwestern Turkey Casserole is a great recipe to use up turkey leftovers!

Southwestern Turkey Casserole

Angela Sellari
This Southwestern Turkey Casserole recipe is a great use of turkey leftovers.
4.90 from 19 votes
Print Recipe Pin Recipe
Prep Time 10 minutes mins
Cook Time 30 minutes mins
Total Time 40 minutes mins
Course Main Course
Cuisine American
Servings 12 servings
Calories 302 kcal

Ingredients
  

  • 2 large onions chopped
  • 1 green pepper chopped
  • 2 tablespoons butter
  • 6 cups cubed cooked turkey
  • 2 cans 10-3/4 ounces each condensed cream of chicken soup, undiluted
  • 2 cups 16 ounces sour cream
  • 1 package 10 ounces frozen chopped spinach, thawed and squeezed dry
  • 2 cups 8 ounces shredded Monterey Jack or cheese blend
  • 1 package 12-1/2 ounces tortilla chips, crushed

Instructions
 

  • Prepare greased 13 inch x 9 inch baking dish. In a medium size pot, saute onions and green pepper in butter until tender. Stir in the turkey, soup, sour cream and spinach. Spoon half of the turkey mixture into the baking dish. Then a layer of cheese and tortilla chips. Repeat layers.
  • Bake casserole, uncovered, at 350 degrees for 25-30 minutes or until bubbly. Let stand for 5 minutes before serving.

Nutrition

Calories: 302kcalCarbohydrates: 8gProtein: 32gFat: 16gSaturated Fat: 8gSodium: 383mgFiber: 1g
Keyword Southwestern Turkey Casserole
Tried this recipe?Let us know how it was!

About Angela SellariContent Creation & Editing

Angela is the founder of About A Mom and currently acts as a content creator and editor-in-chief for the About A Mom Team. She has been a professional blogger for over 10 years. Angela has appeared in numerous TV segments, advertising campaigns and her work has been featured by many top publications. She lives in Tampa, Florida.

Reader Interactions

Published: Nov 12, 2013 | Updated: Oct 27, 2025
4.90 from 19 votes (5 ratings without comment)

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Recipe Rating




  1. Diana C says

    Posted on 11/30 at 2:43 PM

    I love finding new recipes for leftover turkey. I didn’t make a big turkey this year, so don’t have quite 6 cups, but will have to see about this for after Christmas.

    Diana C

    Reply
  2. Jessica Fortner says

    Posted on 12/2 at 3:46 AM

    Oooh, this is perfect for all that leftover turkey and nothing more satisfying than a casserole. Perfect marriage.

    Reply
  3. christina bentz says

    Posted on 12/3 at 7:18 PM

    Is that green bell pepper? I just want to make sure I am getting the right green peppers.

    Reply
    • Angela says

      Posted on 12/3 at 8:01 PM

      Yes, it’s a green bell pepper. Can’t wait to hear how you like this recipe. đŸ™‚

      Reply
  4. Robin says

    Posted on 4/22 at 8:11 PM

    5 stars
    I was looking for a recipe for leftover turkey breast from Easter and found this recipe.I made this tonight and it was delicious. I only made half the recipe, added a can of drained black beans and added some fajita seasoning for more spice. I also mixed the cheese and chips together. It cooked up beautifully and did not fall apart when serving. My son ate three portions. I am giving it 5 stars and adding it to my keeper recipes. Try it, you won’t be disappointed.

    Reply
  5. Dawn Wilson says

    Posted on 11/28 at 7:15 PM

    5 stars
    I added a can of RĂ³tel tomatoes and replaced the bell peppers with a small can of green chilies. Yum!

    Reply
    • Cindy says

      Posted on 11/29 at 1:43 PM

      Hey dawn! Just saw your post from yesterday. I was thinking of doing the exact same thing, nixing the bell pepper and adding a small can of chopped green chilies. Also going to chop a medium tomato as an addition, my kiddos are not fond of Rotel. So yours turned out great?

      Reply
Older Comments
Citrus and Herb Turkey is incredibly moist and flavorful and perfect for your Thanksgiving dinner. If you're looking for a turkey preparation that is a little bit different while still being traditional, this citrus and herb turkey recipe with a lemon-garlic gravy is for you.
Previous Post
Citrus and Herb Turkey Recipe with Lemon-Garlic Gravy
Next Post
Gluten Free Pumpkin Pie

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