• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar

About a Mom

Inspiration for Motherhood

  • Dinner Ideas
    • Main Course
    • Pasta
    • Chicken
    • Casseroles
    • Vegetarian
    • Slow Cooker Recipes
    • Keto
  • Appetizers & Sides
    • Salads & Side Dishes
    • Appetizers
    • Bread
  • Sweet Treats
    • Dessert
    • Baking
    • Cookies
  • Kids Corner
    • Crafts for Kids
    • Kids Fun
    • Activities
    • Learning Activities
    • Food for Kids
  • Mealtime
  • Printables
  • Crafts
  • parenting
  • About
HomeMealtimeRecipesCasseroles

Southwestern Turkey Casserole

4.90 from 19 votes
Angela SellariBy Angela Sellari
Angela Sellari
Angela Sellari Founder of AboutAMom

Angela is the founder of About A Mom and currently acts as a content creator and editor-in-chief for the About A Mom Team. She has been a professional blogger for over 10 years. Angela has appeared…

Expertise: Content Creation & Editing View all posts →
Jump to Recipe

Pretty soon you’ll be wondering what to do with all that leftover Thanksgiving or Christmas turkey.

Southwestern Turkey Casserole in a red dish, with a golden, crispy topping.

Turkey sandwiches are always great, but they get so boring after a couple of days. Instead use some of that leftover turkey to make a delicious meal like this Southwestern Turkey Casserole. Last week Mom and I prepared our Citrus and Herb Turkey, and then used some of the leftovers for this casserole. It was delicious, and I think I might have enjoyed the casserole more than the traditional turkey dinner we ate.

This casserole can be prepared in one large 13 inch x 9 inch baking dish. We opted to make 2 smaller casseroles. One to keep and one to send over to my brother’s house. The recipe can easily be halved – the beauty of a casserole. Since this dish has crushed tortilla chips, I recommend serving the same day it is prepared so the chips keep their crunch. I love that added texture.

Southwestern Turkey Casserole in a red baking dish, topped with golden cheese and crushed tortilla chips.

Ingredients:

  • 2 large onions, chopped
  • 1 green pepper, chopped
  • 2 tablespoons butter
  • 6 cups cubed cooked turkey
  • 2 cans (10-3/4 ounces each) condensed cream of chicken soup, undiluted
  • 2 cups (16 ounces) sour cream
  • 1 package (10 ounces) frozen chopped spinach, thawed and squeezed dry
  • 2 cups (8 ounces) shredded Monterey Jack or cheese blend
  • 1 package (12-1/2 ounces) tortilla chips, crushed

Instructions:

Step 1: Prepare greased 13 inch x 9 inch baking dish. In a medium size pot, saute onions and green pepper in butter until tender. Stir in the turkey, soup, sour cream and spinach. Spoon half of the turkey mixture into the baking dish. Then a layer of cheese and tortilla chips. Repeat layers.

Step 2: Bake casserole, uncovered, at 350 degrees for 25-30 minutes or until bubbly. Let stand for 5 minutes before serving.

Enjoy! What’s your favorite turkey leftovers recipe?

Southwestern Turkey Casserole in a red dish, with a golden, crispy topping.

Southwestern Turkey Casserole

Angela Sellari
Dive into this Southwestern Turkey Casserole recipe! Layered with cheesy turkey & tortilla chips, it's the ultimate comfort for leftovers.
4.90 from 19 votes
Print Recipe Pin Recipe
Prep Time 10 minutes mins
Cook Time 30 minutes mins
Total Time 40 minutes mins
Course Main Course
Cuisine American
Servings 12 servings
Calories 302 kcal

Ingredients
  

  • 2 large onions chopped
  • 1 green pepper chopped
  • 2 tablespoons butter
  • 6 cups cubed cooked turkey
  • 2 cans 10-3/4 ounces each condensed cream of chicken soup, undiluted
  • 2 cups 16 ounces sour cream
  • 1 package 10 ounces frozen chopped spinach, thawed and squeezed dry
  • 2 cups 8 ounces shredded Monterey Jack or cheese blend
  • 1 package 12-1/2 ounces tortilla chips, crushed

Instructions
 

  • Prepare greased 13 inch x 9 inch baking dish. In a medium size pot, saute onions and green pepper in butter until tender. Stir in the turkey, soup, sour cream and spinach. Spoon half of the turkey mixture into the baking dish. Then a layer of cheese and tortilla chips. Repeat layers.
  • Bake casserole, uncovered, at 350 degrees for 25-30 minutes or until bubbly. Let stand for 5 minutes before serving.

Nutrition

Calories: 302kcalCarbohydrates: 8gProtein: 32gFat: 16gSaturated Fat: 8gSodium: 383mgFiber: 1g
Keyword Southwestern Turkey Casserole
Tried this recipe?Let us know how it was!

About Angela SellariContent Creation & Editing

Angela is the founder of About A Mom and currently acts as a content creator and editor-in-chief for the About A Mom Team. She has been a professional blogger for over 10 years. Angela has appeared in numerous TV segments, advertising campaigns and her work has been featured by many top publications. She lives in Tampa, Florida.

Reader Interactions

Published: Nov 12, 2013 | Updated: May 18, 2026
4.90 from 19 votes (5 ratings without comment)

Leave a Comment Cancel reply

Have a question? Use the form below to submit your question or comment. I love hearing from you and seeing what you made!

Recipe Rating




  1. Melissa Au says

    Posted on 11/12 at 6:27 PM

    5 stars
    Wow, this sounds delicious! THanks for sharing.

    Reply
  2. judy gardner says

    Posted on 11/12 at 6:39 PM

    this sounds really good (and so does your turkey recipe)! we always have leftover turkey.

    Reply
  3. Dawn Lopez says

    Posted on 11/12 at 7:21 PM

    5 stars
    Oh ladies, you are killing me! This looks so good I might make it FOR Thanksgiving, LOL! I love the idea of a baked tortilla topping, brilliant!

    Reply
  4. Penelope (NYC Blogger) says

    Posted on 11/12 at 7:48 PM

    It sounds delish! Turkey is always tasty, even as leftovers.

    Reply
  5. Theresa says

    Posted on 11/12 at 8:45 PM

    This looks so yummy! Pity we never have much leftover turkey around here. lol

    Reply
  6. Amanda says

    Posted on 11/12 at 9:32 PM

    I love making casseroles with leftovers! They are perfect to make and put in the freezer for a quick meal!

    Reply
  7. Jennifer says

    Posted on 11/12 at 9:40 PM

    5 stars
    Yummy yum yummy. I am sitting here stuffed, and yet… I would eat this now. lol

    Reply
  8. Kathleen says

    Posted on 11/12 at 9:55 PM

    5 stars
    This sounds very yummy! As a Canadian, my turkey leftovers were gone a month ago but I could easily do this with chicken!

    Reply
  9. Anne says

    Posted on 11/12 at 10:06 PM

    Sounds good, I am always looking for new things to do with left over turkey

    Reply
  10. Nancy Lustri (StyleDecor) says

    Posted on 11/12 at 11:28 PM

    5 stars
    Love baking casserole dishes and this one looks especially tasty! Thanks for sharing!

    Reply
Older Comments
Newer Comments
A whole roasted Citrus and Herb Turkey, golden brown and garnished, on a white platter.
Previous Post
Citrus and Herb Turkey Recipe with Lemon-Garlic Gravy
Gluten Free Pumpkin Pie in a red pie dish, topped with small pastry cutouts.
Next Post
Gluten Free Pumpkin Pie

Primary Sidebar

  • About
  • Contact

Join The Club

Subscribe for inspiration straight to your inbox!

Sign Up

Let's Connect

Back to Top
  • Contact
  • About
  • Privacy
  • Terms
About A Mom is part of Waywith.

Rate This Recipe

Your vote:




A rating is required
A name is required
An email is required

Recipe Ratings without Comment

Something went wrong. Please try again.